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Gene Bio Systems

EIF2S3 Antibody - Cat. #: CSB-PA007528ESR1HU

EIF2S3 Antibody - Cat. #: CSB-PA007528ESR1HU

CSB-PA007528ESR1HU

£289.00 GBP
£289.00 GBP
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Size :50ul

Clone Number:

Aliases:eIF-2-gamma X antibody; eIF-2gA antibody; eIF-2gX antibody; EIF2 antibody; EIF2G antibody; EIF2gamma antibody; EIF2S3 antibody; Eukaryotic translation initiation factor 2 gamma antibody; Eukaryotic translation initiation factor 2 gamma subunit antibody; Eukaryotic translation initiation factor 2 subunit 3 antibody; Eukaryotic translation initiation factor 2 subunit 3 gamma 52kDa antibody; Eukaryotic translation initiation factor 2 subunit gamma X antibody; IF2G_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P41091

Immunogen:Recombinant Human Eukaryotic translation initiation factor 2 subunit 3 protein (173-472AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B (By similarity). Along with its paralog on chromosome Y, may contribute to spermatogenesis up to the round spermatid stage (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:EIF2S3

Research Areas:Epigenetics and Nuclear Signaling

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