EIF2AK3 Monoclonal Antibody

SKU: BT-MCA3889

Size:100μL

Background:The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:EIF2AK3

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:5G5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:EIF2AK3

Immunogen:Purified recombinant fragment of human EIF2AK3 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):125kDa

UniProt accession:Q9NZJ5

Synonyms:PEK, WRS, PERK, EIF2AK3

GeneID:9451