EFNB1 Antibody - Cat. #: CSB-PA007465ESR1HU

SKU: CSB-PA007465ESR1HU

Size :50ul

Clone Number:

Aliases:CFND antibody; CFNS antibody; Craniofrontonasal syndrome (craniofrontonasal dysplasia) antibody; EFL 3 antibody; EFL-3 antibody; EFL3 antibody; EFNB1 antibody; EFNB1_HUMAN antibody; Elk L antibody; ELK ligand antibody; ELK-L antibody; Eph related receptor tyrosine kinase ligand 2 antibody; EPH-related receptor tyrosine kinase ligand 2 antibody; Ephrin-B1 antibody; EPLG2 antibody; LERK 2 antibody; LERK-2 antibody; LERK2 antibody; Ligand of eph related kinase 2 antibody; MGC8782 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P98172

Immunogen:Recombinant Human Ephrin-B1 protein (28-237AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:EFNB1

Research Areas:Neuroscience; Developmental biology; Signal transduction