EEF1E1 Polyclonal Antibody

SKU: E-AB-18404

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: EEF1E1

Target Synonym: AIMP 3;AIMP3;Aminoacyl tRNA synthetase complex interacting multifunctional protein 3;Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3;ARS interacting multifunctional protein 3;EEF1E1;Elongation factor p18;Eukaryotic translation elongation factor 1 epsilon 1;Eukaryotic translation elongation factor 1 epsilon-1;Homolog of rat elongation factor p18;MCA3;Multisynthase complex auxiliary component p18;Multisynthetase complex auxiliary component p18;p18;p18 component of aminoacyl tRNA synthetase complex

Research Areas: Cancer;Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O43324

Accession:

Background: This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Concentration: 1.1 mg/mL

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 20 kDa

ObservedMW: Refer to figures