EDEM1 Polyclonal Antibody

SKU: BT-AP15369

Size:100μL

Background:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3.,

Research_area:Signal transduction

Target_protein:EDEM1

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:ER degradation-enhancing alpha-mannosidase-like 1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q92611; Mouse: Q925U4

Synonyms:ER degradation-enhancing alpha-mannosidase-like 1

GeneID:Human: 9695