E2F4 Antibody - Cat. #: CSB-PA290646

SKU: CSB-PA290646

Size :100ul

Clone Number:

Aliases:E2F 4 antibody; E2F transcription factor 4 antibody; E2F transcription factor 4 p107/p130 binding antibody; E2F-4 antibody; E2F4 antibody; E2F4_HUMAN antibody; p107/p130 binding protein antibody; Transcription factor E2F 4 antibody; Transcription factor E2F4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q16254

Immunogen:Synthesized peptide derived from Human E2F4.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1.

Kathryn M. Kinross, Blood, Aug 2006; 108: 886 - 895.
Dawei Wang, Mol. Cell. Biol., May 2000; 20: 3417 - 3424.
Stephan P. Persengiev, Mol. Cell. Biol., Sep 1999; 19: 6048 - 6056.
Stefan Gaubatz, Mol. Cell. Biol., Feb 2001; 21: 1384 - 1392.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:E2F4

Research Areas:Epigenetics and Nuclear Signaling;Stem cells