E2F-3 (Acetyl Lys168) rabbit pAb

SKU: ES8447

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB: 1:500-10000 ELISA: 1:10000

Immunogen:Synthesized acetyl-peptide from human protein at AA range: 130-200

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):50kD

Human_gene_id:1871

Human_swiss_prot_no:O00716

Subcellular_location:Nucleus.

Other_name:E2F3 KIAA0075

Background:This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013],