DUSP11 Polyclonal Antibody

SKU: E-AB-17232

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: DUSP11

Target Synonym: Dual specificity phosphatase 11;Dual specificity protein phosphatase 11;DUS11;DUSP11;Phosphatase that interacts with RNA/RNP complex 1;PIR1;RNA/RNP complex 1 interacting;RNA/RNP complex interacting phosphatase;RNA/RNP complex-1-interacting phosphatase;RNA/RNP complex1 intereracting phosphatase;Serine/threonine specific protein phosphatase

Research Areas: Epigenetics and Nuclear Signaling;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O75319

Accession:

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism.

Concentration: 1.5 mg/mL

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:30-150

Calculated MW:

ObservedMW: