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GeneBio Systems

DRD4 Polyclonal Antibody

DRD4 Polyclonal Antibody

SKU:E-AB-12360

Regular price £291.00 GBP
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Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:DRD4

Target Synonym:D(2C) dopamine receptor;D(4) dopamine receptor (D(2C) dopamine receptor).;D(4) dopamine receptor;D4 dopamine receptor;D4DR;Dopamine D4 receptor;DRD 4;Drd4;DRD4

Research Areas:Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P21917

Accession:

Background:This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Concentration:0.4 mg/mL

Immunogen:Synthetic peptide of human DRD4

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:30-1:150

Calculated MW:48kDa

ObservedMW:

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