DR6(Phospho-Ser562) Rabbit Polyclonal Antibody

SKU: BT-AP02307

Size:100μL

Background:This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1)| and induces cell apoptosis. Through its death domain| the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein| which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation| and may be involved in inflammation and immune regulation.

Research_area:Cell biology

Target_protein:TNFRSF21

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:DR6

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O75509; Mouse: Q9EPU5

Synonyms:DR6 ;Ser562; Tumor necrosis factor receptor superfamily member 21; Death receptor 6; CD antigen CD358

GeneID:Human: 27242; Mouse: 94185