DOK4 Antibody - Cat. #: CSB-PA548346

SKU: CSB-PA548346

Size :100ul

Clone Number:

Aliases:DOK4Docking protein 4 antibody; Downstream of tyrosine kinase 4 antibody; Insulin receptor substrate 5 antibody; IRS-5 antibody; IRS5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8TEW6

Immunogen:Synthesized peptide derived from internal of Human DOK4.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway By similarity. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.

Favre C., Genes Immun. 4:40-45(2003).
Cai D., J. Biol. Chem. 278:25323-25330(2003).
Loftus B.J., Genomics 60:295-308(1999).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DOK4

Research Areas:Neuroscience;Signal transduction