Disintegrin EC3B Antibody, Biotin conjugated - Cat. #: CSB-PA305523HD01EAH

SKU: CSB-PA305523HD01EAH

Size :50ug

Clone Number:

Aliases:Disintegrin EC3B antibody

Product Type:Polyclonal Antibody

Immunogen Species:Echis carinatus

UniProt ID:P81631

Immunogen:Recombinant Echis carinatus Disintegrin EC3B protein (1-67AA)

Raised in:Rabbit

Species Reactivity:Echis carinatus

Tested Applications:ELISA

Background:Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1). It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins. The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit. The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:

Research Areas:Others