DCTN3 Polyclonal Antibody

SKU: E-AB-14937

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: DCTN3

Target Synonym: DCNT22;DCTN 22;DCTN22;Dctn3;DCTN3;dynactin 3 (p22);dynactin 3;dynactin 3 isoform 1;Dynactin complex subunit 22 kDa subunit;dynactin light chain;Dynactin subunit 3;p22

Research Areas: Cancer;Cell Biology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O75935

Accession:

Background: This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

Concentration: 0.6 mg/mL

Immunogen: Recombinant protein of human DCTN3

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:100-1:300

Calculated MW:

ObservedMW: