DARPP-32 (phospho-Ser97) rabbit pAb

SKU: ES17020

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human;Mouse;Rat

Dilution:WB 1:1000-2000

Immunogen:Synthesized phosho peptide around human DARPP-32 (Ser97)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):30kD

Human_gene_id:84152

Human_swiss_prot_no:Q9UD71

Subcellular_location:Cytoplasm.

Other_name:Protein phosphatase 1 regulatory subunit 1B (DARPP-32) (Dopamine- and cAMP-regulated neuronal phosphoprotein)

Background:This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],