CYP4F2 Antibody - Cat. #: CSB-PA006451LA01HU

SKU: CSB-PA006451LA01HU

Size :50ug

Clone Number:

Aliases:CYP4F2Cytochrome P450 4F2 antibody; EC 1.14.14.1 antibody; 20-hydroxyeicosatetraenoic acid synthase antibody; 20-HETE synthase antibody; Arachidonic acid omega-hydroxylase antibody; CYPIVF2 antibody; Cytochrome P450-LTB-omega antibody; Docosahexaenoic acid omega-hydroxylase antibody; EC 1.14.14.79 antibody; Leukotriene-B(4) 20-monooxygenase 1 antibody; Leukotriene-B(4) omega-hydroxylase 1 antibody; EC 1.14.14.94 antibody; Phylloquinone omega-hydroxylase CYP4F2 antibody; EC 1.14.14.78 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P78329

Immunogen:Recombinant Human Phylloquinone omega-hydroxylase CYP4F2 protein (268-373AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background:Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B(4) omega-hydroxylase by mediating conversion of leukotriene-B(4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B(4) (20-OH LTB4) (PubMed:8026587, PubMed:9799565).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CYP4F2

Research Areas:Others