CYP2C8 Antibody - Cat. #: CSB-PA694882

SKU: CSB-PA694882

Size :100ul

Clone Number:

Aliases:CP2C8_HUMAN antibody; CPC8 antibody; CYP2C8 antibody; CYPIIC8 antibody; Cytochrome P450 2C8 antibody; Cytochrome P450 family 2 subfamily C polypeptide 8 antibody; Cytochrome P450 form 1 antibody; Cytochrome P450 IIC2 antibody; Cytochrome P450 MP-12 antibody; Cytochrome P450 MP-20 antibody; Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 8 antibody; Flavoprotein linked monooxygenase antibody; Microsomal monooxygenase antibody; MP 12/MP 20 antibody; P450 form 1 antibody; P450 IIC2 antibody; P450 MP 12/MP 20 antibody; S mephenytoin 4 hydroxylase antibody; S-mephenytoin 4-hydroxylase antibody; Xenobiotic monooxygenase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P10632

Immunogen:Synthesized peptide derived from internal of Human Cytochrome P450 2C8.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).

Romkes M., Biochemistry 30:3247-3255(1991).
Ged C., Biochim. Biophys. Acta 1088:433-435(1991).
Zeldin D.C., Arch. Biochem. Biophys. 322:76-86(1995).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CYP2C8

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction