CYP2B6 Antibody - Cat. #: CSB-PA289766

SKU: CSB-PA289766

Size :50ul

Clone Number:

Aliases:1,4 cineole 2 exo monooxygenase antibody; 11B1 antibody; CP2B6_HUMAN antibody; CPB 6 antibody; CPB6 antibody; CYP 2B6 antibody; CYP IIB6 antibody; CYP2B antibody; CYP2B6 antibody; CYP2B7 antibody; CYP2B7P antibody; CYPIIB6 antibody; Cytochrome P450 2B6 antibody; Cytochrome P450 family 2 subfamily B antibody; Cytochrome P450 family 2 subfamily B polypeptide 6 antibody; Cytochrome P450 IIB1 antibody; Cytochrome P450 phenobarbital inducible antibody; Cytochrome P450 subfamily IIB (phenobarbital inducible) antibody; Cytochrome P450 subfamily IIB (phenobarbital inducible) polypeptide 6 antibody; Cytochrome P450 subfamily IIB polypeptide 6 antibody; EFVM antibody; IIB1 antibody; P450 antibody; P450 IIB1 antibody; P450IIB1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P20813

Immunogen:Synthetic peptide of Human CYP2B6

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CYP2B6

Research Areas:Cardiovascular;Metabolism;Signal transduction