CYP2A6 Antibody - Cat. #: CSB-PA909765

SKU: CSB-PA909765

Size :100ul

Clone Number:

Aliases:Coumarin 7 hydroxylase antibody; Coumarin 7-hydroxylase antibody; CP2A6_HUMAN antibody; CPA6 antibody; CYP2A antibody; CYP2A3 antibody; CYP2A6 antibody; CYPIIA6 antibody; Cytochrome P450 2A6 antibody; Cytochrome P450 IIA3 antibody; Cytochrome P450 subfamily IIA (phenobarbital inducible) polypeptide 6 antibody; Cytochrome P450(I) antibody; Cytochrome P450; family 2 subfamily A polypeptide 6 antibody; Flavoprotein linked monooxygenase antibody; P450C2A antibody; P450PB antibody; Xenobiotic monooxygenase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P11509

Immunogen:Synthesized peptide derived from N-terminal of Human Cytochrome P450 2A6.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

Miles J.S., ic Acids Res. 17:2907-2917(1989).
Yamano S., Biochemistry 29:1322-1329(1990).
Saito S., J. Hum. Genet. 48:249-270(2003).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CYP2A6

Research Areas:Cancer?Cardiovascular;Metabolism;Signal transduction