CYH2 Rabbit Polyclonal Antibody

SKU: BT-AP08847

Size:100μL

Background:The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif| a central Sec7 domain| and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization| the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity| and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1| ARF3| and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.

Research_area:Signal transduction

Target_protein:CYTH2

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:CYH2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):44000

UniProt accession:Human: Q99418; Mouse: P63034; Rat: P63035

Synonyms:CYH2

GeneID:Human: 9266; Mouse: 19158; Rat: 116692