Cyclin C(Phospho Ser275) Polyclonal Antibody

SKU: BT-AP00479

Size:100μL

Background:The protein encoded by this gene is a member of the cyclin family of proteins. The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II. The level of mRNAs for this gene peaks in the G1 phase of the cell cycle. Two transcript variants encoding different isoforms have been found for this gene.

Research_area:Cell biology; Epigenetics and nuclear signaling

Target_protein:CCNC

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Cyclin-C

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):33243

UniProt accession:Human: P24863; Mouse: Q62447; Rat: P39947

Synonyms:Cyclin-C; CCNC; Cyclin-C; SRB11 homolog; hSRB11

GeneID:Human: 892; Mouse: 51813