CUX1 antibody , Cat. # FNab02083

SKU: FNab02083

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions(MARs)(5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor(TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator(By similarity).

Immunogen:cut-like homeobox 1

Synonyms:CASP, CCAAT displacement protein, CDP, CDP/Cut, CDP1, Clox, COY1, cut like homeobox 1, CUTL1, CUX, Cux/CDP, CUX1, GOLIM6, Homeobox protein cut like 1, Homeobox protein cux 1, Nbla10317, p100, p110, p200, p75

Observed MW:80 kDa

Uniprot ID:P39880

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF, IHC, IP

Recommended dilution:WB: 1:1000-1:3000; IP:1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100

Gene ID:1523

Research Area:Neuroscience, Cardiovascular, Metabolism, Developmental biology