CUL5 Antibody - Cat. #: CSB-PA835890ESR1HU

SKU: CSB-PA835890ESR1HU

Size :50ul

Clone Number:

Aliases:CUL 5 antibody; CUL-5 antibody; CUL5 antibody; CUL5_HUMAN antibody; Cullin 5 antibody; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody; Cullin-5 antibody; Cullin5 antibody; VACM 1 antibody; VACM-1 antibody; VACM1 antibody; Vasopressin activated calcium mobilizing receptor 1 antibody; Vasopressin activated calcium mobilizing receptor antibody; Vasopressin-activated calcium-mobilizing receptor 1 antibody; Vasopressin-activated calcium-mobilizing receptor-1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q93034

Immunogen:Recombinant Human Cullin-5 protein (1-300AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CUL5

Research Areas:Cell biology