GeneBio Systems
CSTB Polyclonal Antibody
CSTB Polyclonal Antibody
SKU:E-AB-13179
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Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: CSTB
Target Synonym: CHROW21;CPI B;CPI-B;CST 6;CST6;CSTB;Cystatin B (stefin B);Cystatin B;Cystatin-B;CYTB;CYTB;EPM1;EPM1A;Liver thiol proteinase inhibitor;PME;Stefin-B;STF B;STFB;ULD
Research Areas: Cancer;Cell Biology
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: P04080
Accession:
Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Concentration: 0.9 mg/mL
Immunogen: Synthetic peptide of human CSTB
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
