CROT rabbit pAb

SKU: ES6668

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Immunogen:Synthesized peptide derived from CROT . at AA range: 190-270

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):72kD

Human_gene_id:54677

Human_swiss_prot_no:Q9UKG9

Subcellular_location:Peroxisome .

Other_name:CROT; COT; Peroxisomal carnitine O-octanoyltransferase; COT

Background:This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009],