CRCP Antibody, Biotin conjugated - Cat. #: CSB-PA005945LD01HU

SKU: CSB-PA005945LD01HU

Size :50ug

Clone Number:

Aliases:Calcitonin gene related peptide receptor component antibody; Calcitonin gene related peptide receptor component protein antibody; Calcitonin gene-related peptide-receptor component protein antibody; CGRP receptor component protein antibody; CGRP-RCP antibody; CGRP-receptor component protein antibody; CGRPRCP antibody; CRCP antibody; DNA-directed RNA polymerase III subunit RPC9 antibody; HsC17 antibody; RCP antibody; RCP9 antibody; RNA polymerase III subunit C9 antibody; RPC9_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O75575

Immunogen:Recombinant Human DNA-directed RNA polymerase III subunit RPC9 protein (1-115AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CRCP

Research Areas:Neuroscience; Cardiovascular; Signal transduction