CP51A Polyclonal Antibody

SKU: BT-AP08048

Size:100μL

Background:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Research_area:Cancer; Cardiovascular; Metabolism; Signal transduction; Neuroscience

Target_protein:CYP51A1

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Lanosterol 14-alpha demethylase

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q16850; Mouse: Q8K0C4; Rat: Q64654

Synonyms:Lanosterol 14-alpha demethylase ;LDM;EC 1.14.13.70;CYPLI;Cytochrome P450 51A1;Cytochrome P450-14DM;Cytochrome P45014DM;Cytochrome P450LI;Sterol 14-alpha demethylase

GeneID:Human: 1595