COPE Antibody - Cat. #: CSB-PA03669A0Rb

SKU: CSB-PA03669A0Rb

Size :50ug

Clone Number:

Aliases:1110005D17Rik antibody; Coatomer epsilon subunit antibody; Coatomer protein complex subunit epsilon antibody; Coatomer subunit epsilon antibody; COPE antibody; COPE_HUMAN antibody; Cope1 antibody; Epsilon coat protein antibody; Epsilon COP antibody; Epsilon COP I antibody; Epsilon subunit of coatomer protein complex antibody; Epsilon-coat protein antibody; Epsilon-COP antibody; FLJ13241 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O14579

Immunogen:Recombinant Human Coatomer subunit epsilon protein (2-308AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Background:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:COPE

Research Areas:Signal transduction