COMMD5 antibody , Cat. # FNab01851

SKU: FNab01851

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:May modulate activity of cullin-RING E3 ubiquitin ligase(CRL) complexes(PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis(By similarity). Down-regulates activation of NF-kappa-B(PubMed:15799966).

Immunogen:COMM domain containing 5

Synonyms:

Observed MW:25-28 kDa

Uniprot ID:Q9GZQ3

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:2000

Gene ID:54951

Research Area:Signal Transduction, Metabolism, Epigenetics