GeneBio Systems
CLK2 Polyclonal Antibody
CLK2 Polyclonal Antibody
SKU:E-AB-53303
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Size::120μL
Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Polyclonal Antibodies
Abbreviation:CLK2
Target Synonym:CDC like kinase 2;CDC-like kinase 2;CLK 2;CLK kinase;CLK2;Clk2 Scamp3;CLK2;Dual specificity protein kinase CLK2;hCLK 2;hCLK2;Tu52
Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Signal Transduction
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human;Mouse
Application:IHC
Isotype:IgG
Clonality:Polyclonal
Clone NO.:
UNIProt ID:P49760
Accession:
Background:This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.
Concentration:0.5 mg/mL
Immunogen:Synthetic peptide of human CLK2
Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification method:Antigen affinity purification
Dilution:IHC 1:30-1:150
Calculated MW:
ObservedMW:
