Claudin 1 Polyclonal Antibody

SKU: E-AB-30939

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: Claudin-1

Target Synonym: Claudin-1;Claudin1;CLD 1;CLD1;CLD1;CLDN 1;Cldn1;ILVASC;SEMP 1;SEMP1;Senescence associated epithelial membrane protein 1;Senescence associated epithelial membrane protein;Senescence-associated epithelial membrane protein

Research Areas: Cancer;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC-p;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O95832

Accession:

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from the C-terminal region of human Claudin-1

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000

Calculated MW: 23kDa

ObservedMW: 22kDa