CHIT1 Monoclonal Antibody

SKU: BT-MCA4304

Size:100μL

Background:CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50 kDa secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.

Research_area:Immunology

Target_protein:CHIT1

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:1D9G2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CHIT1

Immunogen:Purified recombinant fragment of CHIT1 (aa22-137) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):52kDa

UniProt accession:Q13231

Synonyms:Chitotriosidase, CHI3, CHIT, FLJ00314, MGC125322, CHIT1

GeneID:1118