CHD8 Polyclonal Antibody

SKU: BT-AP14939

Size:100μL

Background:This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research_area:Epigenetics and nuclear signaling

Target_protein:CHD8

applications:IHC-p, IF

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Chromodomain-helicase-DNA-binding protein 8

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9HCK8; Mouse: Q09XV5; Rat: Q9JIX5

Synonyms:Chromodomain-helicase-DNA-binding protein 8 ;CHD-8;EC 3.6.4.12;ATP-dependent helicase CHD8;Helicase with SNF2 domain 1

GeneID:Human: 57680