CDH12 Polyclonal Antibody

SKU: E-AB-19682

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CDH12

Target Synonym: Br cadherin;BR-cadherin;Brain cadherin;CAD12_HUMAN;cadherin 12 (N cadherin 2);Cadherin 12;Cadherin 12 precursor;Cadherin 12 type 2 (N cadherin 2);Cadherin 12 type 2;Cadherin neural type 2;Cadherin-12;CDH12;CDHB;FLJ34857;N cadherin 2;N-cadherin 2;Neural type cadherin 2;Neuronal cadherin 2

Research Areas: Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P55289

Accession:

Background: This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.

Concentration: 1.74 mg/mL

Immunogen: Synthetic peptide of human CDH12

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:100

Calculated MW:

ObservedMW: