CDC25A Polyclonal Antibody

SKU: E-AB-70140

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:CDC25A

Target Synonym:Cdc 25a;CDC25A;CDC25A2;CDC25A2 CAG isoform;Cell division cycle 25 homolog A (S. pombe);Cell division cycle 25A;Cell division cycle 25A isoform a;Cell division cycle 25A isoform b;D9Ertd393e;Dual specificity phosphatase Cdc25A;M phase inducer phosphatase 1;M-phase inducer phosphatase 1;MGC115549;MPIP1

Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P30304,P48965,P48964

Accession:

Background:CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Concentration:0.96 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse Cdc25A

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:1000;IHC 1:500-1:1000

Calculated MW:65-70kDa

ObservedMW:70kDa