CD8A Monoclonal Antibody

SKU: BT-MCA3028

Size:100μL

Background:The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

Research_area:Immunology, Cancer

Target_protein:CD8A

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:6A9A5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CD8A

Immunogen:Purified recombinant fragment of human CD8A (AA: extra 22-182) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):25.7kDa

UniProt accession:P01732

Synonyms:CD8, MAL, p32, Leu2

GeneID:925