CD49D Monoclonal Antibody

SKU: BT-MCA4307

Size:100μL

Background:The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.

Research_area:Others

Target_protein:CD49D

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:7E4C5

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:CD49D

Immunogen:Purified recombinant fragment of human CD49D (AA: extra 833-977) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):114.9kDa

UniProt accession:P13612

Synonyms:ITGA4, IA4

GeneID:3676