CD242 rabbit pAb

SKU: ES8799

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Mouse

Dilution:IHC-p 1:50-200, ELISA 1:10000-20000

Immunogen:Synthetic peptide from human protein at AA range: 141-190

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:3386

Human_swiss_prot_no:Q14773

Subcellular_location:[Isoform Long]: Cell membrane; Single-pass type I membrane protein.; [Isoform Short]: Secreted .; Cell membrane ; Single-pass type I membrane protein .

Other_name:Intercellular adhesion molecule 4 (ICAM-4;Landsteiner-Wiener blood group glycoprotein;LW blood group protein;CD antigen CD242)

Background:This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],