CD170 Monoclonal Antibody

SKU: BT-MCA4028

Size:100μL

Background:This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Research_area:Others

Target_protein:CD170

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:3F5A3

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:CD170

Immunogen:Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):60.7kDa

UniProt accession:O15389

Synonyms:SIGLEC5, OBBP2, CD33L2, OB-BP2, SIGLEC-5

GeneID:8778