CD13 /ANPEP Monoclonal Antibody

SKU: AN200163P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:ANPEP

Target Synonym:LAP;ANPEP;APN;CD13;GP150;LAP1;P150;PEPN;Aminopeptidase N;AP-M;AP-N;CD13 antigen;CD13APN;PEPNhAPN;gp150;Alanyl (membrane) aminopeptidase;Alanyl aminopeptidase;Aminopeptidase M;AMPN;AP M;AP N;CD 13;hAPN;LAP 1;Microsomal aminopeptidase;Myeloid plasma membrane glycoprotein CD13

Research Areas:Immunology;Stem Cells

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB;IP

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:5A3

UNIProt ID:P15144

Accession:

Background:Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

Concentration:1 mg/mL

Immunogen:Recombinant Human CD13 /ANPEP Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;IP 5-10 μL/mg of lysate

Calculated MW:150 kDa

ObservedMW:150 kDa