CCL5 Polyclonal Antibody

SKU: E-AB-17864

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CCL5

Target Synonym: Beta chemokine RANTES;Beta chemokine RANTES precursor;C C motif chemokine 5;CCL 5;CCL5;CCL5;Chemokine (C C motif) ligand 5;Chemokine CC Motif Ligand 5;D17S136E;EoCP;Eosinophil chemotactic cytokine;MGC17164;RANTES(4-68);Regulated upon activation normally T expressed and presumably secreted;SCYA 5;SCYA5;SIS delta;SIS-delta;SISd;Small inducible cytokine A5 (RANTES);Small inducible cytokine A5;Small inducible cytokine subfamily A (Cys Cys) member 5;Small-inducible cytokine A5;T cell specific protein p288 ;T cell specific RANTES protein;T cell-specific protein P228;T-cell-specific protein RANTES;TCP 228;TCP228

Research Areas: Cancer;Cardiovascular;Immunology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P13501

Accession:

Background: This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.

Concentration: 2 mg/mL

Immunogen: Synthetic peptide of human CCL5

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:40-1:200

Calculated MW:

ObservedMW: