CATSPER4 Antibody, FITC conjugated - Cat. #: CSB-PA745763LC01HU

SKU: CSB-PA745763LC01HU

Size :50ug

Clone Number:

Aliases:CATSPER4Cation channel sperm-associated protein 4 antibody; CatSper4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q7RTX7

Immunogen:Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CATSPER4

Research Areas:Neuroscience