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GeneBio Systems

Cathepsin L Polyclonal Antibody

Cathepsin L Polyclonal Antibody

SKU:AN007170L

Regular price £109.00 GBP
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Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:Cathepsin L

Target Synonym:CATL;CATL1;CTSL;CTSL1;Cathepsin L1;Cathepsin L1 light chain;CathepsinL;FLJ31037;MEP;MGC123162;Major excreted protein;cathepsin L;cb15;ctsl1b;hgg1

Research Areas:Cancer;Neuroscience;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P07711

Accession:

Background:The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Human Cathepsin L protein expressed by Mammalian

Buffer:PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:IHC 1:500-1:1000

Calculated MW:

ObservedMW:

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