Caspase-9 Monoclonal Antibody

SKU: AN007230L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:Caspase-9

Target Synonym:Apoptosis related cysteine peptidase;Apoptotic protease-activating factor 3;Caspase 9 apoptosis related cysteine peptidase;Caspase 9 Dominant Negative;Caspase 9c;Caspase-9 subunit p10;ICE LAP6;ICE like apoptotic protease 6;ICE-like apoptotic protease 6;protein phosphatase 1;regulatory subunit 56;RNCASP9;MCH;Apoptotic protease Mch;PPP1R;ICE-LAP;CASP9;APAF-3;APAF3;ICE-LAP6;MCH6;PPP1R56;caspase-9;Caspase 9;CASP-9;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3 (APAF-3);ICE-like apoptotic protease 6 (ICE-LAP6)

Research Areas:Cell Biology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB

Isotype:IgG2a

Clonality:Monoclonal

Clone NO.:3B6

UNIProt ID:P55211

Accession:

Background:Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Concentration:1 mg/mL

Immunogen:Recombinant Human Caspase-9 protein expressed by E.coli

Buffer:PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Purification method:Protein A/G Purification

Dilution:WB 1:250-1:500

Calculated MW:46 kDa

ObservedMW:35 kDa;47 kDa