CASP-7 Monoclonal Antibody

SKU: BT-MCA2044

Size:100μL

Background:This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research_area:Others

Target_protein:CASP-7

applications:WB, IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:4D10B2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CASP-7

Immunogen:Purified recombinant fragment of human CASP-7 (AA: 29-198) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):34.3kDa

UniProt accession:P55210

Synonyms:MCH3, CMH-1, LICE2, CASP7, ICE-LAP3

GeneID:840