CAMK2A Polyclonal Antibody

SKU: E-AB-19660

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CAMK2A

Target Synonym: Alpha CaMKII;Calcium calmodulin dependent protein kinase II;Calcium/calmodulin dependent protein kinase II alpha B subunit;Calcium/calmodulin dependent protein kinase type II alpha chain;Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha;Calcium/calmodulin-dependent protein kinase II alpha;Calcium/calmodulin-dependent protein kinase II-alpha;Calcium/calmodulin-dependent protein kinase type II subunit alpha;Calcium/calmodulin-dependent protein kinase type IIA;CaM kinase II alpha chain;CaM kinase II alpha subunit;CaM kinase II subunit alpha;CaMK II alpha subunit;CaMK-II subunit alpha;Camk2a;CAMKA;CaMKII;CaMKIINalpha;EC 2.7.11.17;KCC2A;KIAA0968;MGC123320;MGC139375;MGC155201;mKIAA0968;PK2CDD;PKCCD;R74975;zgc:112538;zgc:123320

Research Areas: Cancer;Cardiovascular;Metabolism;Neuroscience;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9UQM7

Accession:

Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Concentration: 0.8 mg/mL

Immunogen: Synthetic peptide of human CAMK2A

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:40-1:200

Calculated MW:

ObservedMW: