Calpain 2 (Phospho Ser50) rabbit pAb

SKU: ES20175

Size: 100μL

Source:Rabbit

Applications:WB; ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB 1:1000-2000 ELISA 1:5000-20000

Immunogen:Synthesized peptide derived from human Calpain 2 (Phospho Ser50)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):69kD

Human_gene_id:824

Human_swiss_prot_no:P17655

Subcellular_location:Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding.

Other_name:Calpain-2 catalytic subunit (EC 3.4.22.53;Calcium-activated neutral proteinase 2;CANP 2;Calpain M-type;Calpain large polypeptide L2;Calpain-2 large subunit;Millimolar-calpain;M-calpain)

Background:The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],