CALHM1 rabbit pAb

SKU: ES20805

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF

Reactivity:Human;Rat

Dilution:WB: 1:500-1000 IHC: 1:200-500

Immunogen:Synthetic Peptide of CALHM1 AA range: 204-254

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:

Observed_band(KD):40kD

Human_gene_id:255022

Human_swiss_prot_no:Q8IU99

Subcellular_location:Cell membrane; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein . Colocalizes with HSPA5 at the endoplasmic reticulum (PubMed:18585350). Localizes to the basolateral membrane of epithelial cells including taste cells (By similarity). .

Other_name:Calcium homeostasis modulator protein 1; Protein FAM26C

Background:calcium homeostasis modulator 1(CALHM1) Homo sapiens This gene encodes a calcium channel that plays a role in processing of amyloid-beta precursor protein. A polymorphism at this locus has been reported to be associated with susceptibility to late-onset Alzheimer's disease in some populations, but the pathogenicity of this polymorphism is unclear.[provided by RefSeq, Mar 2010],