CAC1G rabbit pAb

SKU: ES10475

Size: 100μL

Source:Rabbit

Applications:IHC;IF

Reactivity:Human;Rat

Dilution:IHC-p 1:50-300

Immunogen:Synthesized peptide derived from human protein . at AA range: 360-440

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):261kD

Human_gene_id:8913

Human_swiss_prot_no:O43497

Subcellular_location:Cell membrane ; Multi-pass membrane protein . Cytoplasm .

Other_name:

Background:calcium voltage-gated channel subunit alpha1 G(CACNA1G) Homo sapiens Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011],