C8orf4 Polyclonal Antibody

SKU: E-AB-18766

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: C8orf4

Target Synonym: C8orf4;CH004;Chromosome 8 open reading frame 4;Human thyroid cancer 1;MGC22806;TC-1;TC1;Thyroid cancer protein 1;Uncharacterized protein C8orf4

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Signal transduction;Stem cells

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9NR00

Accession:

Background: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

Concentration: 0.96 mg/mL

Immunogen: Fusion protein of human C8orf4

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:40-1:200

Calculated MW:

ObservedMW: