C8AP2 rabbit pAb

SKU: ES17928

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human; Mouse

Dilution:WB 1：500-2000

Immunogen:Synthesized peptide derived from human C8AP2 AA range: 1155-1205

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:9994

Human_swiss_prot_no:Q9UKL3

Subcellular_location:Cytoplasm. Nucleus. Nucleus, PML body. Mitochondrion. Exported from the nucleus to the mitochondria upon FAS activation.

Other_name:

Background:This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008],